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CJC-1295 No DAC
Growth

Buy CJC-1295 No DAC — 5 mg Lyophilized Vial

≥98% HPLC purity · lot-matched CoA · sealed under nitrogen

GHRH-receptor investigations built for cross-compound potency mapping.

CJC-1295 is a growth-hormone-releasing hormone (GHRH) analog engineered for extended stability. Two variants dominate the research literature: CJC-1295 "No DAC" — a shorter-acting GHRH analog — and CJC-1295 "with DAC" — which includes a Drug Affinity Complex that binds albumin and dramatically extends circulating half-life.

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Bac-water math

Reconstitution volumes

Volumes of bacteriostatic water required to dissolve each vial at common research concentrations.

Vialat 2 mg/mLat 5 mg/mLat 10 mg/mL
5 mg2.50 mL1 mL0.50 mL
10 mg5 mL2 mL1 mL

Numbers are calculated from the stated vial mass. Verify against the supplier's instructions for your specific research protocol.

In stock

Available sizes

At a glance

Key facts

  • Two research variants: No DAC (short-acting) and with DAC (long-acting)
  • GHRH analog — different receptor than ghrelin-pathway secretagogues
  • Frequently paired with ipamorelin for dual-pathway GH research
  • Well-documented pharmacokinetic profiles in both variants
Primer

Mechanism in the literature

Both variants bind the GHRH receptor in the anterior pituitary, stimulating growth-hormone release. The "with DAC" version carries a lysine-reactive maleimide linker that covalently binds serum albumin, extending half-life from hours (No DAC) to days (with DAC).

From the same shelf

Often paired with

Buyers viewing CJC-1295 No DAC typically also consider Ipamorelin, GHRP-2 and GHRP-6. Each is in stock, sealed under nitrogen with a lot-matched CoA.

What it's used for

Research use-cases

  • Two research variants: No DAC (short-acting) and with DAC (long-acting)
  • GHRH analog — different receptor than ghrelin-pathway secretagogues
  • Frequently paired with ipamorelin for dual-pathway GH research
  • Well-documented pharmacokinetic profiles in both variants
Protocol notes

Handling in the lab

No DAC protocols typically use multi-daily dosing to match natural GH pulsatility. With DAC protocols use once-weekly schedules due to the extended half-life. Reconstitute in BAC water and aliquot.

Pairing notes

Stacking and paired-compound work

CJC-1295 + Ipamorelin is the standard dual-pathway GH research combination. Tesamorelin is an alternative GHRH-analog for researchers who prefer not to work with DAC-linked compounds.

Storage and shelf-life

Lyophilized powder is stable at ambient shipping temperatures. Once reconstituted with bacteriostatic water, store at 2–8 °C and use within 28 days. For long-term storage of unreconstituted vials, freeze at −20 °C and protect from light.

Questions we get

Frequently asked

What does "DAC" mean?

Drug Affinity Complex — a chemical modification that allows the peptide to covalently bind serum albumin, extending its circulating half-life from hours to days.

Should I choose DAC or No DAC?

Depends on protocol design. No DAC is used when mimicking natural pulsatile GH release; with DAC is used for sustained-level research where weekly dosing is preferable.

How does it differ from ipamorelin?

CJC-1295 is a GHRH analog. Ipamorelin is a ghrelin-receptor agonist. They work on different receptors and are often combined.

Is it stable long-term?

Unreconstituted vials are stable at −20 °C for extended periods. Reconstituted solutions follow standard peptide handling — 2–8 °C, 28 days.

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