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Epitalon
Longevity

Buy Epitalon — 10 mg Lyophilized Vial

≥98% HPLC purity · lot-matched CoA · sealed under nitrogen

Mapped against mitochondrial turnover endpoints — anti-ageing pathway work.

Epitalon (Epithalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed from pineal-gland extracts. It is one of the most studied peptides in telomere-biology and circadian-regulation research, with a multi-decade literature primarily from Russian and Eastern European groups.

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Bac-water math

Reconstitution volumes

Volumes of bacteriostatic water required to dissolve each vial at common research concentrations.

Vialat 2 mg/mLat 5 mg/mLat 10 mg/mL
10 mg5 mL2 mL1 mL
50 mg25 mL10 mL5 mL

Numbers are calculated from the stated vial mass. Verify against the supplier's instructions for your specific research protocol.

In stock

Available sizes

At a glance

Key facts

  • Tetrapeptide: Ala-Glu-Asp-Gly
  • Studied in telomere-biology, circadian, and longevity research
  • Developed by Prof. Khavinson at the St. Petersburg Institute of Bioregulation
  • Available in 10 mg and 50 mg research vials
Primer

Mechanism in the literature

Research describes epitalon as a telomerase-activating peptide — upregulating telomerase reverse transcriptase (TERT) expression in somatic cells. It is also reported to normalize melatonin rhythms and modulate pineal-axis function in aging models.

From the same shelf

Often paired with

Buyers viewing Epitalon typically also consider FOXO4-DRI, ACE-031 and NA-Epitalon. Each is in stock, sealed under nitrogen with a lot-matched CoA.

What it's used for

Research use-cases

  • Tetrapeptide: Ala-Glu-Asp-Gly
  • Studied in telomere-biology, circadian, and longevity research
  • Developed by Prof. Khavinson at the St. Petersburg Institute of Bioregulation
  • Available in 10 mg and 50 mg research vials
Protocol notes

Handling in the lab

Both injectable and intranasal research routes appear in the literature. Short courses (10–20 days) are more common than continuous protocols.

Pairing notes

Stacking and paired-compound work

Epitalon is commonly studied alongside Pinealon and other short bioregulator peptides from the Khavinson series.

Storage and shelf-life

Lyophilized powder is stable at ambient shipping temperatures. Once reconstituted with bacteriostatic water, store at 2–8 °C and use within 28 days. For long-term storage of unreconstituted vials, freeze at −20 °C and protect from light.

Questions we get

Frequently asked

Is Epitalon the same as Epithalon?

Yes — two transliterations of the same Russian-developed tetrapeptide.

What is NA-Epitalon?

N-acetylated Epitalon — a modified form with improved stability profile in some research protocols.

How long are research courses typically run?

Short pulsed courses (10–20 days, 1–2× annually in animal models) dominate the literature, not continuous dosing.

What is telomerase activation?

Upregulation of the enzyme that extends telomeres at chromosome ends — a central mechanism studied in cellular aging.

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