Buy MOTS-c Online — 3 sizes (10 mg–40 mg)
Regenerative-signalling work — built around collagen remodelling and vascular endpoints.
MOTS-c is a 16-amino-acid mitochondrial-derived peptide encoded in the 12S rRNA region of the mitochondrial genome. It is one of the most interesting entries in the "mitokine" class — peptides produced by mitochondria that signal metabolic state to the rest of the cell.
Vial sizes and price per mg
Up to 27% cheaper per mgReconstitution volumes
Volumes of bacteriostatic water required to dissolve each vial at common research concentrations.
| Vial | at 2 mg/mL | at 5 mg/mL | at 10 mg/mL |
|---|---|---|---|
| 10 mg | 5 mL | 2 mL | 1 mL |
| 20 mg | 10 mL | 4 mL | 2 mL |
| 40 mg | 20 mL | 8 mL | 4 mL |
Numbers are calculated from the stated vial mass. Verify against the supplier's instructions for your specific research protocol.
Mechanism in the literature
MOTS-c modulates AMPK signaling and has been studied as a regulator of insulin sensitivity, glucose homeostasis, and exercise-response biology. Research describes it translocating to the nucleus under metabolic stress to regulate gene expression.
Research use-cases
- Mitochondrial-derived peptide (a "mitokine")
- Encoded within the 12S rRNA region of mtDNA
- Studied in insulin-sensitivity, exercise, and longevity models
- Available in 10, 20, and 40 mg research vials
Often paired with
Buyers viewing MOTS-c typically also consider BPC-157, VIP and Bronchogen. Each is in stock, sealed under nitrogen with a lot-matched CoA.
Handling in the lab
Research protocols typically use multi-weekly injection schedules. Reconstitute in BAC water; 20 mg vial in 2 mL yields 10 mg/mL stock.
Stacking and paired-compound work
MOTS-c is frequently paired with NAD+ and SS-31 in mitochondrial-biology research stacks.
Frequently asked
What is a mitokine?
A signaling peptide produced by mitochondria — MOTS-c and humanin are the best-characterized members of this class.
How was MOTS-c discovered?
Through mining short ORFs in the mitochondrial genome — a 2015 paper from the Lee lab at USC put it on the research map.
What is its connection to exercise?
Research reports increased MOTS-c release during exercise and some evidence that exogenous administration mimics exercise-like metabolic endpoints.
Why multiple vial sizes?
Longer studies at higher concentrations use the 40 mg vial; shorter pilots use 10 mg.
