Buy PT-141 — 10 mg Lyophilized Vial
Cellular-senescence research — exploring mTOR / AMPK signalling balance.
PT-141 (bremelanotide) is a synthetic melanocortin-receptor agonist developed from the α-MSH peptide lineage. It is one of the best-known entries in the melanocortin-pathway research literature, with a focus on central-nervous-system activation.
Reconstitution volumes
Volumes of bacteriostatic water required to dissolve each vial at common research concentrations.
| Vial | at 2 mg/mL | at 5 mg/mL | at 10 mg/mL |
|---|---|---|---|
| 10 mg | 5 mL | 2 mL | 1 mL |
Numbers are calculated from the stated vial mass. Verify against the supplier's instructions for your specific research protocol.
Key facts
- MC4R-selective melanocortin agonist
- CNS-active — crosses the blood-brain barrier
- Studied in both sexual-response and appetite-regulation research
- Shorter half-life than melanotan analogs
Mechanism in the literature
PT-141 acts primarily on MC4R (melanocortin-4 receptor) in the central nervous system. MC4R is a key node in both energy-balance and central-sexual-response circuits — the basis for the two main lines of PT-141 research.
Often paired with
Buyers viewing PT-141 typically also consider Glutathione, RU-58841 (Topical) and P21. Each is in stock, sealed under nitrogen with a lot-matched CoA.
Research use-cases
- MC4R-selective melanocortin agonist
- CNS-active — crosses the blood-brain barrier
- Studied in both sexual-response and appetite-regulation research
- Shorter half-life than melanotan analogs
Handling in the lab
Research protocols commonly reconstitute in BAC water and use subcutaneous administration. Pulsed protocols dominate over continuous dosing.
Stacking and paired-compound work
PT-141 is typically studied alone rather than in stacks. Melanotan I/II are related compounds but have different receptor selectivity profiles.
Storage and shelf-life
Lyophilized powder is stable at ambient shipping temperatures. Once reconstituted with bacteriostatic water, store at 2–8 °C and use within 28 days. For long-term storage of unreconstituted vials, freeze at −20 °C and protect from light.
Frequently asked
Is PT-141 the same as Vyleesi?
Vyleesi is a pharmaceutical formulation of bremelanotide (PT-141). Research-grade material sold here is for laboratory use only.
How does it differ from Melanotan II?
Melanotan II is a broader-spectrum melanocortin agonist that also activates MC1R (pigmentation). PT-141 is more MC4R-selective and does not drive pigmentation to the same degree.
What is MC4R?
Melanocortin-4 receptor — a central-nervous-system target involved in appetite regulation and sexual-response circuits.
What is its half-life?
Short — hours rather than days. Research protocols reflect this with pulsed dosing.
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