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N-Acetyl Semax Amidate
Cognitive

Buy N-Acetyl Semax Amidate — 30 mg Lyophilized Vial

≥98% HPLC purity · lot-matched CoA · sealed under nitrogen

Exploring working-memory behavioural models — cerebrovascular research.

Semax is a synthetic heptapeptide derived from ACTH(4-10), developed in Russia as a nootropic and neuroprotective research compound. It has a substantial literature base in cognitive, stroke-recovery, and BDNF-modulation research.

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Reconstitution volumes

Volumes of bacteriostatic water required to dissolve each vial at common research concentrations.

Vialat 2 mg/mLat 5 mg/mLat 10 mg/mL
30 mg15 mL6 mL3 mL

Numbers are calculated from the stated vial mass. Verify against the supplier's instructions for your specific research protocol.

At a glance

Key facts

  • Derived from ACTH(4-10) — the non-corticotropic fragment
  • Strong BDNF/NGF upregulation in research models
  • N-Acetyl Semax Amidate version offers extended stability
  • One of the most extensively studied Russian research nootropics
Primer

Mechanism in the literature

Semax upregulates BDNF and NGF expression in rodent brain research, and modulates dopaminergic and serotonergic signaling. It has been studied across learning, memory, and post-ischemic-recovery models.

From the same shelf

Often paired with

Buyers viewing N-Acetyl Semax Amidate typically also consider PE-22-28, Selank and DSIP (Delta Sleep-Inducing Peptide). Each is in stock, sealed under nitrogen with a lot-matched CoA.

What it's used for

Research use-cases

  • Derived from ACTH(4-10) — the non-corticotropic fragment
  • Strong BDNF/NGF upregulation in research models
  • N-Acetyl Semax Amidate version offers extended stability
  • One of the most extensively studied Russian research nootropics
Protocol notes

Handling in the lab

Intranasal delivery is standard in Russian research protocols. Injectable routes also appear. N-Acetyl Semax Amidate is preferred for longer research windows.

Pairing notes

Stacking and paired-compound work

Often compared to or paired with Selank in cognitive-research designs.

Storage and shelf-life

Lyophilized powder is stable at ambient shipping temperatures. Once reconstituted with bacteriostatic water, store at 2–8 °C and use within 28 days. For long-term storage of unreconstituted vials, freeze at −20 °C and protect from light.

Questions we get

Frequently asked

What is N-Acetyl Semax Amidate?

A stabilized form of Semax with both N-terminal acetylation and C-terminal amidation — improved half-life for longer protocols.

How does Semax compare to Selank?

Semax is more cognitive/neurotrophic; Selank is more anxiolytic. Related research lineages but different research applications.

What is BDNF?

Brain-Derived Neurotrophic Factor — a key growth factor in neuronal survival and synaptic plasticity. Semax is one of the more potent research peptides for BDNF upregulation.

Injectable or intranasal?

Intranasal is standard in the Russian research tradition; injectable protocols also appear.

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