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Sermorelin
Growth

Buy Sermorelin Online — 3 sizes (2 mg–10 mg)

≥98% HPLC purity · lot-matched CoA · sealed under nitrogen

Mapped to comparative secretagogue studies — somatotropic signalling work.

Sermorelin is a truncated GHRH (1-29) analog, one of the shortest GHRH fragments that retains full biological activity. It is studied as a "natural" GH-axis research tool — driving endogenous GH release via the GHRH receptor.

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Vial sizes and price per mg

Up to 40% cheaper per mg
SizePrice$ / mgBest valueBuy
2 mg$35.99$18.00Buy →
5 mg$62.99$12.60Buy →
10 mg$107.99$10.80BestBuy →
Bac-water math

Reconstitution volumes

Volumes of bacteriostatic water required to dissolve each vial at common research concentrations.

Vialat 2 mg/mLat 5 mg/mLat 10 mg/mL
2 mg1 mL0.40 mL0.20 mL
5 mg2.50 mL1 mL0.50 mL
10 mg5 mL2 mL1 mL

Numbers are calculated from the stated vial mass. Verify against the supplier's instructions for your specific research protocol.

Primer

Mechanism in the literature

Sermorelin binds the GHRH receptor in the anterior pituitary, stimulating endogenous growth-hormone release. Its short sequence (29 residues) is the minimal GHRH fragment that preserves receptor activity.

What it's used for

Research use-cases

  • GHRH (1-29) — the minimal active GHRH fragment
  • Stimulates endogenous GH release
  • Shorter half-life than tesamorelin or CJC-1295
  • Long history in GH-axis research
From the same shelf

Often paired with

Buyers viewing Sermorelin typically also consider CJC-1295 No DAC, Tesamorelin and Kisspeptin-10. Each is in stock, sealed under nitrogen with a lot-matched CoA.

Protocol notes

Handling in the lab

Reconstitute under sterile technique with bacteriostatic water. Typical volumes range from 1–3 mL depending on the target working concentration. Swirl gently — do not shake — to avoid peptide shearing.

Pairing notes

Stacking and paired-compound work

Sometimes combined with ghrelin agonists (ipamorelin) for dual-pathway GH research.

Questions we get

Frequently asked

How does sermorelin compare to tesamorelin?

Tesamorelin is a stabilized GHRH (1-44) analog with better half-life. Sermorelin is the shorter GHRH (1-29) fragment — simpler structure but less protease-resistant.

How does it compare to CJC-1295?

CJC-1295 is GHRH (1-29) with additional stabilizing modifications (plus DAC in the longer-acting version). Sermorelin is the unmodified baseline.

Why short half-life?

Sermorelin lacks the protease-resistance modifications present in tesamorelin and CJC-1295. Half-life is measured in minutes rather than hours.

Is it still used in research?

Yes — its short action profile is desirable in some research designs precisely because it mimics native GHRH pulsatility.

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